Potential impacts of synthetic food dyes on activity and attention in children: a review of the human and animal evidence

Current evidence from studies in humans, largely from controlled exposure studies in children, supports a relationship between food dye exposure and adverse behavioral outcomes in children, both with and without pre-existing behavioral disorders. There appears to be considerable interindividual variability in the sensitivity to synthetic food dyes. While there were a range of results in the studies we identified, the majority reported at least some evidence of an association, including higher quality studies.

https://ehjournal.biomedcentral.com/articles/10.1186/s12940-022-00849-9

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